Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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5,941 – 5,955 of 60,541 results

5,941

Medchemexpress LLC HY-W018025 100mg Medchemexpress, 5,6-Dihydroxyindole CAS:3131-52-0 Purity:>98%

Medchemexpress, HY-W018025 100mg 5,6-Dihydroxyindole CAS:3131-52-0 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,942

Apexbio Technology LLC Efinaconazole 164650-44-6 5mg

Efinaconazole (CAS 164650-44-6) is a small-molecule inhibitor targeting the cytochrome P450 enzyme lanosterol 14 -demethylase It is designed to inhibit this enzyme thereby disrupting fungal cell membrane biosynthesis by blocking the conversion of lanosterol to ergosterol Efinaconazole exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies Efinaconazole demonstrates antifungal activity against dermatophytes implicated in onychomycosis primarily Trichophyton species with an IC50 typically ranging from 0 003 to 0 03 g/mL Based on these pharmacological properties Efinaconazole holds research potential in the evaluation of antifungal efficacy resistance mechanisms and pharmacological profiles relevant to dermatological fungal infections

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5,943

Medchemexpress LLC HY-N0087 5mg , Gambogic Acid CAS:2752-65-0 Purity:>98%

HY-N0087 5mg Gambogic Acid CAS: 2752-65-0 Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,944

Medchemexpress LLC NNC 55-0396 | 357400-13-6 | 99.0% | C30H40Cl2FN3O2 | 1 MG

NNC 55-0396 is a highly selective T-type calcium channel blocker with an IC50 value of 6.8 μM for Cav3.1 T-type channels. It can be utilized for research related to neurological diseases.

Highly selective T-type calcium channel blocker
IC50 value of 6.8 μM for Cav3.1 T-type channels
Useful for neurological disease research
Suppresses tremor in GABAA subunit α1-null mice and harmaline mouse models

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5,945

Cayman Chemical Lipid 10, Purity: ≥95%, CAS: 2430034-02-7, 25 mg

An ionizable cationic lipid (pKa = 6.2-6.5); LNPs containing lipid 10 and encapsulating CKAP5 siRNA reduce its gene expression and protein levels in vitro and selectively reduce cell viability in a variety of genetically unstable cancer cell lines; LNPs containing lipid 10 and encapsulating CKAP5 siRNA reduce tumor growth and increase survival in an NCI/ADR-RES human ovarian cancer mouse xenograft model

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5,946

Medchemexpress LLC Pyridoxamine 5′-phosphate | 529-96-4 | 98.9% | 1 MG

Pyridoxamine 5′-phosphate is the active form of vitamin B6, bound to phosphoric acid. It acts as a co-factor for various enzymes, a central metabolite, a potent antioxidant, a vitamin B6 vitamer, and an enzyme substrate.

Active form of vitamin B6
Bound to phosphoric acid
Co-factor for various enzymes
Central metabolite
Potent antioxidant
Vitamin B6 vitamer
Enzyme substrate
Interconvertible with pyridoxal 5'-phosphate hydrate
Intended for research use only
Appearance: Solid
Color: White to yellow
Molecular weight: 248.17
Formula: C8H13N2O5P
Structure classification: Alkaloids, pyridine alkaloids
Initial source: Endogenous metabolite, human gut microbiota metabolites

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5,947

Cayman Chemical N,N-Diethylpentylone (hydrochloride), Purity: ≥98%, CAS: 17763-15-4, 5 mg

A cathinone whose physiological and toxicological actions have not been characterized

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5,948

TARGETMOL CHEMICALS INC KDM4D-IN-1 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KDM4D-IN-1 is a KDM4D inhibitor (IC50 0.41±0.03 uM). purity: 99%

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5,949

Cayman Chemical WYneN, Purity: ≥95%, CAS: 3052492-38-0, 50 mg

A chemoselective probe for protein sulfenylation; selective for sulfenylated proteins over DNTB and 4-DPS; binds to sulfenylated proteins in live cells and can then be conjugated to azide-containing fluorescent probes for detection

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5,950

Cayman Chemical BP-1-102, Purity: ≥98%, CAS: 1334493-07-0, 25 mg

An inhibitor of STAT3; binds to STAT3 (Kd = 504 nM) and inhibits STAT3 binding to an IL-6R/gp130 peptide in a fluorescence polarization assay (IC50 = 4.1 µM); decreases viability and proliferation of STAT3-dependent NIH3T3/v-Src, MDA-MB-231, PANC-1, DU145 and A549 cancer cells, but not STAT3-independent NIH3T3, NIH3T3/vRas, TE-71, and A2780S cancer cells at 10-30 µM; reduces tumor growth and inhibits expression of the STAT3-dependent genes encoding c-Myc, survivin, Bcl-xL, cyclin D1, and VEGF in MDA-MB-231 and A549 mouse xenograft models at 1 and 3 mg/kg

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5,951

Cayman Chemical SOBRAC, Purity: ≥95%, CAS: 362678-28-2, 1 mg

An inhibitor of acid ceramidase (Ki = 29.7 nM)

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5,952

Cayman Chemical [Gly8,36,Glu22]-GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (acetate), Purity: ≥98%, 5 mg

A GLP-1 derivative and fragment of dulaglutide

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5,953

Medchemexpress LLC 3-Propylxanthine | 41078-02-8 | MFCD00043205 | 98.7% | 194.19 | C8H10N4O2 | 5 MG

Enprofylline is a xanthine-derived research compound that functions as a selective and competitive adenosine A2B receptor antagonist and a phosphodiesterase inhibitor. It is provided as a solid for laboratory use and has defined solubility, purity, and storage properties appropriate for in vitro and in vivo research applications.

Acts as an adenosine A2B receptor antagonist and phosphodiesterase inhibitor.
Molecular formula C8H10N4O2; molecular weight 194.19.
High purity (98.7%) suitable for research use.
White to light yellow solid; pack size 5 MG.
Soluble in DMSO at 62.5 MG/ML; ultrasonic assistance may be required.
Store solid at 4°C protected from light; in solution store -80°C (6 months) or -20°C (1 month).

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5,954

Cayman Chemical ANTIBODY IPG-4 AM 500ug

A cell-permeable fluorescent potassium indicator; has been used to detect intracellular potassium; binds to potassium (Kd = 7 mM); ex/em = 525/545 nm

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5,955

Medchemexpress LLC Transthyretin/TTR H 2ug

Recombinant human transthyretin (TTR) expressed in HEK293 cells with C-terminal human Fc and C-Myc tags. Supplied as a purified protein suitable for biochemical assays, interaction studies, and research into amyloidosis and Alzheimer's disease. Packaged at 2 μg for small-scale experiments.

Human TTR expressed in mammalian cells for native folding and post-translational modifications.
C-terminal Fc and Myc tags to facilitate detection and purification.
Suitable for biochemical assays and protein-protein interaction studies.
Useful for amyloidosis and Alzheimer's disease research models.
Supplied in a small pack size for pilot or optimization experiments.

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Bioactive Small Molecules

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Medchemexpress LLC HY-W018025 100mg Medchemexpress, 5,6-Dihydroxyindole CAS:3131-52-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N0087 5mg , Gambogic Acid CAS:2752-65-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NNC 55-0396 | 357400-13-6 | 99.0% | C30H40Cl2FN3O2 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyridoxamine 5′-phosphate | 529-96-4 | 98.9% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 3-Propylxanthine | 41078-02-8 | MFCD00043205 | 98.7% | 194.19 | C8H10N4O2 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Transthyretin/TTR H 2ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More